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KMID : 1033820000010010065
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Journal of Artificial Heart Research
2000 Volume.1 No. 1 p.65 ~ p.72
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Animal condition monitoring following the implantation of an implantable VAD
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Lee Kyoung-Kap
Cheong Jong-Tae
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Abstract
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When an implantable VAD was implanted to an animal, it was monitored the conditions of the animals by measuring clinicopathological factors such as CBC, GOT, SDH, Total bilirubin, BUN, creatinine and LDH. We found that the clinicophthological examination was agreed with the findings from autopsy. Values in RBC and PCV increased temporarily after the operation, but it took about 7 days for them to return to the normal level. WBC gradually increased initially, but decreased around the 5-7 days after the operation. Values of Fib and GOT were increased and stayed at high levels for the whole period. SDH in the goat showed high values between the 13 and 15 days following the operation and, at that time, GOT also increased up. Total bilirubin, which was excreted from the liver cell, was gradually increased in the sheep since the 14 days following the operation. BUN in the goat was ever increasing and LDH was seen to be initially increased and then gradually decreased. It was observed at the autopsy the degeneration of the liver and heart, and the local necrosis caused by the blocking of the vessels in the kidney.
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KEYWORD
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implantable VAD, clinicopathological examination, CBC, GOT, SDH, Total bil. BUN, Creatinine, LDH
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